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Antiresorptive Agents Prevent or Treat Osteoporosis

Web  Med Education

"Advancing standards of Education & Healthcare Practice"

Dr. Maninder Ahuja
Vice President Elect FOGSI(2013)
Ahuja Hospital & Infertility Centre

"I have learned that success is to be measured not so much by the position that one has reached in life as by the obstacles which he has overcome while trying to succeed." - -Booker T. Washington


Support your bones- Role of Biomarkers in Management of Osteoporosis

This is one of series of case discussion on osteoporosis.


Osteoporosis is a "Silent Thief and a killer". It  is a disease in which the density and quality of bone are reduced, leading to reduced strength of skeleton and increased risk of fracture, Osteoporosis is a global problem which is increasing in significance as the population of the world both grows and ages.

Worldwide, lifetime risk for osteoporotic fractures in women is 30-50%. In men risk is 15-30%. According to World Health Organization (WHO), osteoporosis is second only to cardiovascular disease as a global healthcare problem and medical studies show a 50-year-old woman has a similar lifetime risk of dying from hip fracture as from breast cancer.(1) By 2050, the worldwide incidence of hip fracture in men is projected to increase by 310% and 240% in women.

In India men are osteoporotic 10-15 years earlier than their western counterparts.

Fractures because of osteoporosis are a huge economical loss for society, person  and Government and still under diagnosed, undertreated and not prevented

Despite the fact that one osteoporotic fracture can cause not only decreased QOL, but also increased mortality and morbidity, so far we are just treating fractures and not osteoporosis, it is duty of all Gynecologists also to learn to treat and follow up patients of osteoporosis at the same time following them for various other co morbidities.

Compliance treatment strategies and Role of BTM ( Biochemical Bone turnover markers) is not clear and that angle would be covered.

Case 1

A 60 years woman comes with H/O joint aches and pains and pain back.
She has a family H/0 fragility fracture in mother.
Her height has decreased in the last year by 2 cm.